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Toward Therapeutic Strategies to Directly Inhibition of Transcription Factors

Now we can inhibit Transcription Factors from binding to DNA, leading cells give up cancer behavior

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INCURIX Science

We develop direct inhibitors of Transcription Factors, the ultimate target of cancer treatment

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Myc ICX-101
Myc ICX-101 Myc ICX-101

ICX-101:
Myc inhibitor

Myc onco-driver has great potential as a therapeutic intervention for cancer. 

ICX-101 directly blocks the Myc-Max complex from binding to DNA binding domain.


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STAT3 ICX-201
STAT3 ICX-201 STAT3 ICX-201​

ICX-201:
STAT3 inhibitor

It directly inhibits STAT3, one of the key transcription factors that promote cancer progression and immune suppression.

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AR ICX-301​
AR ICX-301​ AR ICX-301

ICX-301:
AR inhibitor

It targets the interaction between androgen receptor and its consensus DNA sequence, so with little concerns related to hormonal therapy or refractory responses from AR variants.

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