Now we can inhibit Transcription Factors from binding to DNA, leading cells give up cancer behavior
We develop direct inhibitors of Transcription Factors, the ultimate target of cancer treatment
Myc onco-driver has great potential as a therapeutic intervention for cancer.
ICX-101 directly blocks the Myc-Max complex from binding to DNA binding domain.
It directly inhibits STAT3, one of the key transcription factors that promote cancer progression and immune suppression.
It targets the interaction between androgen receptor and its consensus DNA sequence, so with little concerns related to hormonal therapy or refractory responses from AR variants.
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